Mr Thompson, just 33, who weighed 65-stone, was found dead inside his flat in Dover, Kent, by police, fire crews and the ambulance service this morning.
Firefighters and police officers took several hours to remove his body.
Mr Thompson shot to fame earlier this year when he appeared on ITV’s This Morning begging for help to lose weight, after being bedbound for more than a year.
Tributes have been paid to him today.
Craig Chapman said: “I have just seen that Carl Thompson has sadly died. I’ve known Carl many years and (he) was a very good friend of mine when I lived in Dover. I used to play pool and have a few pints with him when he was mobile. I can’t believe it, so tragic.”
Lyn Garret tweeted: “RIP UK heaviest man Carl Thompson. Gentle Giant. Dover is in shock.”
Neighbour Ronald Williams said the operation to remove Carl’s body “took emergency crews several hours.”
A police spokesman said: “Kent Police were called at 10.38am to a property in Dofras Place, Dover, following reports that a man in his 30s had died.
“Officers do not believe the death to be suspicious. The coroner will be notified.”
Mr Thompson, who was single and lived alone, made national headlines earlier this year after it was revealed his excessive binge eating had caused his weight to rocket to 65 stone.
After he featured on This Morning, in a TV interview live from his bed, he was swamped with offers to help him lose weight.
He said he had always had a bad relationship with food and, as a child, would sneak downstairs in the night and raid the kitchen cupboards in his childhood home in Lydden.
He said: “I was only about three or four and no one knew why I did it. I would just eat anything out of the cupboards.”
During the TV appearance, Dr Dawn Harper suggested he was being “killed with kindness” by people still prepared to get his daily junk food dose to him.
Dr Dawn also said when discussing with Carl his diet before interview that he had mentioned his mother’s passing as a reason for his enormous weight gain.
Carl has put on 30 stone since his mother died in 2012 and he said it was one of the reasons he carried on eating as a way to cope with the grief which he still wasn’t over.
Sunday Express is Lesotho's only Sunday newspaper. Published every Sunday and distributed nationwide. News: firstname.lastname@example.org | Advertising: email@example.com | Telephone: +266 2231 5356